Job Title: Research Scientist, Bioanalytics (21091-09BR)

Description:

The Bioanalytical Development group within the Preclinical Sciences Department is seeking a Research Scientist to develop and implement assays to investigate in vivo pharmacokinetics, pharmacodynamics, and immunogenicity in support of non-clinical and clinical programs for the development of biologics.

Major Duties and Responsibilities:

• Develop, validate and implement PK, PD and immunogenicity assays to support non-clinical and clinical programs.
• Perform sample analysis, analyze, QC, and present bioanalytical data in the form of bioanalytical reports and PowerPoint presentations.
• Write analytical procedures and validation/method development reports for internal and CRO transfer support.
• Serve as a CRO monitor including:
• Method transfer, validation, and sample analysis management.
• Regulatory document review including: validation protocols, validation reports, analytical procedures, raw data, and bioanalytical reports.
• Track and adhere to timelines. Trouble-shoot to ensure that timelines are met without compromising data quality.
• Collaborate with cross-functional research, analytical, pharmacology, toxicology, and clinical staff.

Job Requirements:

• An advanced degree in the biological sciences, chemistry or related discipline with at least 4 years industry experience.
• Experience in the area of assay development to support drug development required.
• Hands on proficiency with immunoassay techniques, ELISA, ECLA, protein conjugation, FACS, qPCR required.
• Experience with Meso Scale Discovery, SoftmaxPro, JMP and WinNonlin software strongly preferred.
• Experience managing multiple projects in a fast-paced environment required.
• Strong organizational skills and attention to detail are required. Experience working in a GLP environment will be considered.
• Excellent analytical skills, superior written and oral communication skills, as well as demonstrated ability to work both independently and in team setting required.

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. EOE